Individuals with “crowded” optic disc are also considered at greater risk for NAION compared to the general population; however, evidence is insufficient to support screening of prospective users of PDE5 inhibitors, including CIALIS, for this uncommon condition. Dosing Guidelines Typical Cialis dosages will differ depending on the conditions it’s prescribed to treat as well as other factors. Patients who demonstrate hemodynamic instability on alpha-blocker therapy alone are at increased risk of symptomatic hypotension with concomitant use of PDE5 inhibitors. Therefore, treatments for erectile dysfunction, including CIALIS, should not be used in men for whom sexual activity is inadvisable as a result of their underlying cardiovascular status. Cialis is a brand-name prescription medication. The results showed the combination to be even more effective than either medication alone. Safety of combined use of PDE5 inhibitors and alpha-blockers may be affected by other variables, including intravascular volume depletion and other antihypertensive drugs.The recommended starting dose of CIALIS for once daily use is mg, taken at approximately the same time every day, without regard to timing of sexual activity. The CIALIS dose for once daily use may be increased . Cialis mg tablet Medication name Uses Other uses How to use Side effects Precautions Drug interactions Overdose Notes Missed dose Storage Important note Information last revised August Copyright (c) First Databank, Inc. Dosing Guidelines Cialis is a prescription medication containing the active ingredient tadalafil. Cialis belongs to a group of medications known as phosphodiesterase-5 (PDE-5) inhibitors. Healthcare providers commonly prescribe tadalafil to treat erectile dysfunction (ED).