Just visit a participating pharmacy. We considered cost, medications available, and whether generic versions were offered to help reduce costs. How oral medicines differ Each oral medicine for ED has a slightly different chemical makeup. Often, these are prescribed for chest pain called angina. They enhance the effects of a chemical the body makes that relaxes muscles in the penis, called nitric oxide. Now, the Drug Enforcement Agency DEA has proposed new rules that will require an in-person visit for anything more than a day supply of controlled substances to be filled by an online pharmacy. Cialis tadalafil : This ED medication works with the same principle as Viagra, but lasts up to 36 hours.Brand name: $ to $1, for ten to thirty 10 mg tablets Generic: $ to $ for ten 10 mg tablets But your out-of-pocket cost for Levitra may depend on a few . Oral medicines for ED usually work well and cause few side effects. The four main medicines taken by mouth for erectile dysfunction are: Avanafil (Stendra). Sildenafil . No, vardenafil isn’t available over the counter (OTC). This is because it has some risks, like low blood pressure and painful erection, that your provider will want to .