It might work longer if you have mild to moderate erectile dysfunction. Insurance: If you plan to use insurance, make sure the online provider accepts it. Kidney disease, severe or Liver disease, severe—Use with caution. Yes, ED pills can cause side effects. This information is reviewed by a licensed practitioner who will assess your eligibility for the medication.Sildenafil is used to treat erectile dysfunction (ED) and to reduce blood pressure in pulmonary arterial hypertension (PAH). It is taken when needed for ED and daily for PAH. A headache, stomach upsets, and flushing are the main side effects, and it should not be taken within 24 hours of a nitrate. 5. Tips. Strengths: 25 mg, 50 mg, mg; Brand: Viagra. Form: oral tablet; Strengths: 25 mg, 50 mg, mg; Adult dosage (ages 18–64 years) Typical dosage: 50 mg, taken as needed about 1 hour before. The four main medicines taken by mouth for erectile dysfunction are: Avanafil (Stendra). Sildenafil (Viagra). Tadalafil (Cialis). Vardenafil. These medicines are called PDE5 inhibitors. They enhance the effects of a chemical the body makes that relaxes muscles in the penis, called nitric oxide.