To work, it requires sexual stimulation as well. The FDA has also approved tadalafil for treatment of both benign prostatic hypertrophy and erectile dysfunction where the two conditions co-exist. Side Effects Common side effects of Cialis include the following: Headache. Tadalafil does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus HIV. This increased blood flow can cause an erection.As needed for ED: 5 to 20 mg by mouth as a one-time dose, with a maximum of one dose in 24 hours. Effects may last up to 36 hours. Daily dosing for ED: or 5 mg by mouth daily. For daily dosing, the maximum dose is 5 mg per day. The medication should be taken once daily at about the same time every day to maintain a consistent level of. Free Coupon. No Insurance Needed. Find Lowest Price How much does tadalafil cost without insurance? The cost of tadalafil without insurance starts at $* for 20mg and . Compare prices and print coupons for Tadalafil (Cialis) (Generic Cialis) and other drugs at CVS, Walgreens, and other pharmacies. Prices start at $