This site is intended only for U. In vivo studies: No significant interactions were shown with tolbutamide mg or warfarin 40 mg , both of which are metabolized by CYP2C9. During 3 to 6 months of double-blind treatment or longer-term 1 year , open-label studies, few patients withdrew from active treatment for any reason, including lack of effectiveness. Especially tell your healthcare provider if you take any of the following: medicines called nitrates medicines called guanylate cyclase stimulators such as Adempas riociguat medicines called alpha-blockers, such as Hytrin terazosin HCl , Flomax tamsulosin HCl , Cardura doxazosin mesylate , Minipress prazosin HCl , Uroxatral alfuzosin HCl , Jalyn dutasteride and tamsulosin HCl , or Rapaflo silodosin. Efficacy Results from Controlled Clinical Studies The effect on one of the major end points, maintenance of erections after penetration, is shown in Figure 6, for the pooled results of 5 fixed-dose, dose-response studies of greater than one month duration, showing response according to baseline function. Similar values for pharmacokinetic parameters were seen in normal volunteers and in the patient population, using a population pharmacokinetic approach.The Savings Offer and Program expire on 12/31/ For further information, call , visit test1.ru, or write: Viatris Inc., P.O. Box , Mission, KS . Typical dosing for Sildenafil (Viagra) The typical dose is to take 50 mg of sildenafil (Viagra) by mouth, about 1 hour before sex, as needed. The maximum . The maximum dose of Viagra is mg each day. Doses above the maximum dose, such as mg per day, will increase the risk of side effects. And in .